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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PCYT1A
All Species:
18.48
Human Site:
S352
Identified Species:
29.05
UniProt:
P49585
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49585
NP_005008.2
367
41731
S352
P
C
S
P
A
N
L
S
R
H
K
A
A
A
Y
Chimpanzee
Pan troglodytes
XP_001143741
320
37092
W306
K
Q
S
P
L
K
G
W
A
R
C
R
D
F
R
Rhesus Macaque
Macaca mulatta
XP_001090055
338
38695
S324
V
A
S
H
H
P
S
S
A
R
I
K
L
F
P
Dog
Lupus familis
XP_535776
367
41764
S352
P
S
S
P
A
N
L
S
R
H
K
A
A
A
Y
Cat
Felis silvestris
Mouse
Mus musculus
P49586
367
41648
S352
S
S
S
P
A
S
L
S
R
C
R
A
V
T
C
Rat
Rattus norvegicus
P19836
367
41662
S352
S
S
S
P
A
S
L
S
R
C
K
A
V
T
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517894
294
33692
S279
P
S
S
P
A
N
L
S
R
H
K
A
A
A
C
Chicken
Gallus gallus
XP_422725
367
42078
R352
S
S
P
A
N
R
S
R
N
E
S
A
V
T
Y
Frog
Xenopus laevis
NP_001089299
367
41920
S352
P
A
S
P
G
R
H
S
R
P
T
A
A
T
Y
Zebra Danio
Brachydanio rerio
NP_001018571
359
41135
F343
F
F
T
S
S
P
F
F
S
P
H
S
G
S
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647621
526
58183
G470
M
A
E
K
L
S
G
G
S
G
S
G
S
S
G
Honey Bee
Apis mellifera
XP_395764
403
46370
S382
K
T
G
R
F
E
Y
S
Q
S
N
Y
Y
L
S
Nematode Worm
Caenorhab. elegans
P49583
362
41751
E342
V
V
E
Q
K
I
V
E
K
K
E
V
V
K
K
Sea Urchin
Strong. purpuratus
XP_001180754
425
48260
V372
G
L
G
Q
A
S
L
V
V
R
D
D
D
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P13259
424
49388
S391
N
T
N
T
N
S
D
S
D
S
N
T
N
S
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
58.5
60.7
96.4
N.A.
96.1
96.4
N.A.
77.3
89
86.3
76.2
N.A.
36.1
46.4
37.8
45.4
Protein Similarity:
100
69.2
71.6
98
N.A.
97.5
97.2
N.A.
78.1
95
91.2
84.1
N.A.
46
62
52.3
60
P-Site Identity:
100
13.3
13.3
93.3
N.A.
46.6
53.3
N.A.
86.6
13.3
53.3
0
N.A.
0
6.6
0
13.3
P-Site Similarity:
100
13.3
13.3
93.3
N.A.
60
60
N.A.
86.6
13.3
53.3
33.3
N.A.
20
13.3
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
34.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
20
0
7
40
0
0
0
14
0
0
47
27
20
0
% A
% Cys:
0
7
0
0
0
0
0
0
0
14
7
0
0
0
20
% C
% Asp:
0
0
0
0
0
0
7
0
7
0
7
7
14
0
0
% D
% Glu:
0
0
14
0
0
7
0
7
0
7
7
0
0
7
7
% E
% Phe:
7
7
0
0
7
0
7
7
0
0
0
0
0
14
0
% F
% Gly:
7
0
14
0
7
0
14
7
0
7
0
7
7
0
7
% G
% His:
0
0
0
7
7
0
7
0
0
20
7
0
0
0
7
% H
% Ile:
0
0
0
0
0
7
0
0
0
0
7
0
0
0
0
% I
% Lys:
14
0
0
7
7
7
0
0
7
7
27
7
0
7
7
% K
% Leu:
0
7
0
0
14
0
40
0
0
0
0
0
7
7
0
% L
% Met:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
0
7
0
14
20
0
0
7
0
14
0
7
0
0
% N
% Pro:
27
0
7
47
0
14
0
0
0
14
0
0
0
0
7
% P
% Gln:
0
7
0
14
0
0
0
0
7
0
0
0
0
0
0
% Q
% Arg:
0
0
0
7
0
14
0
7
40
20
7
7
0
0
7
% R
% Ser:
20
34
54
7
7
34
14
60
14
14
14
7
7
20
7
% S
% Thr:
0
14
7
7
0
0
0
0
0
0
7
7
0
27
7
% T
% Val:
14
7
0
0
0
0
7
7
7
0
0
7
27
0
0
% V
% Trp:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
7
0
0
0
0
7
7
0
27
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _